Skin-delivered hormones via gels or creams offer flexible titration, but require consistent application sites and precautions to avoid transfer to others.
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When stopping hormone therapy, gradual tapering can minimize rebound symptoms, allowing the body to adjust smoothly while monitoring for issues.
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Bone protection in transgender youth blockers may require DEXA monitoring and adequate nutrition, with plans to optimize density during later therapy.
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Early menopause or ovarian insufficiency often benefits from hormone therapy until average menopausal age to protect heart, bone, and cognitive health.
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